Brett Favre threw a 32-yard touchdown pass to Greg Lewis in the back of the end zone with 2 seconds left to lift Minnesota to a 27-24 victory over the stunned San Francisco 49ers on Monday.
An official review upheld Lewis' unbelievable catch, sending the sellout crowd into a frenzy. Some of the fans had already left after two unsuccessful possessions against a stingy 49ers defence.
But they were successful in the end, during an 80-yard drive that took 87 of the 89 seconds that remained when the unbeaten Vikings got the ball back.
Favre completed six passes during the drive and finished 24-for-46 for 301 yards, two scores and his first interception.
Lions 19, Redskins 14
At Detroit, the Lions ended their 19-game losing streak by holding off the Redskins.
Matthew Stafford threw a 21-yard touchdown pass to Bryant Johnson in the first quarter and the two connected to draw a key penalty to set up a TD in the fourth.
The Lions (1-2) had not won since Dec. 23, 2007 and their skid matched the second longest in NFL history.
Eagles 34, Chiefs 14
At Philadelphia, getting significant contributions from their youngsters and backups, the Eagles routed Kansas City in Michael Vick's return to the NFL.
Kevin Kolb threw for 327 yards and two touchdowns, LeSean McCoy had 84 yards rushing and one TD, and DeSean Jackson and Brent Celek each had 100-plus yards receiving and one score for Philadelphia (2-1).
Jets 24, Titans 17
At East Rutherford, Mark Sanchez threw two touchdown passes and ran for another to become the first rookie quarterback to start a season with wins in his first three games, helping the Jets to their fourth 3-0 start in franchise history.
New York's defence, which allowed its first touchdowns of the season, turned up the pressure in the fourth quarter and stopped Kerry Collins, who was 0 for his last 13 as the Titans lost a third straight match.
Packers 36, Rams 17
At St. Louis, Aaron Rodgers threw two touchdown passes and ran for another as the Packers sent the Rams to their 13th straight loss.
The Rams have lost 30 of 35 since the start of the 2007 season.
Rodgers and Greg Jennings hooked up on passes of 50 and 53 yards that set up touchdowns for Green Bay.
Ravens 34, Browns 3
At Baltimore, Joe Flacco threw for a career-high 342 yards and Willis McGahee scored two more touchdowns as the Ravens cruised to victory.
After unbeaten Baltimore held the Browns to 78 yards while building a 20-0 halftime lead, Cleveland coach Eric Mangini pulled quarterback Brady Quinn in favour of Derek Anderson. The switch did nothing to turn around the fortune of a team that has been outscored 95-29 this season.
Jaguars 31, Texans 24
At Houston, Maurice Jones-Drew scored three touchdowns to lead the Jaguars over the mistake-prone Texans.
Jones-Drew scored the go-ahead touchdown on an 8-yard run early in the fourth quarter and finished with 119 yards rushing.
Giants 24, Buccaneers 0
At Tampa, Florida, Eli Manning threw for two touchdowns to help the Giants remain unbeaten with a rout of the winless Bucs.
It was the Giants' first shutout since a 36-0 home victory over Washington in October 2005. They hadn't blanked an opponent on the road since beating
Philadelphia 23-0 in November 1983.
Tampa Bay has lost seven straight dating to an 0-4 December that cost it a playoff berth last season.
Patriots 26, Falcons 10
At Foxborough, Massachusetts, Tom Brady threw for 277 yards and Fred Taylor ran for 105 in New England's win over the Falcons.
Brady threw a 36-yard touchdown pass to Chris Baker and Taylor ran for an 8-yard score.
Broncos 23, Raiders 3
At Oakland, California, Kyle Orton threw a touchdown pass to Brandon Marshall, and rookie Knowshon Moreno ran for 90 yards and a score to lead the Broncos to their third straight win.
Chargers 23, Dolphins 13
At San Diego, Philip Rivers helped the Chargers end a seven-game losing streak against Miami.
Rivers scored on a 5-yard scramble late in the third quarter to highlight a victory over the winless Dolphins, who lost quarterback Chad Pennington to a shoulder injury early in the second half.
In the shotgun on third-and-goal, Rivers couldn't find a receiver and the pocket collapsed, so he sprinted up the middle and into the end zone for a 10-6 lead.
Saints 27, Bills 7
At Orchard Park, Will Smith had an interception and a sack to help New Orleans shut down Buffalo.
The Saints prevented the Bills from mustering any type of a threat through three quarters.
The Bills offense sputtered, and Terrell Owens was held without a catch, to end a 185-game streak that had been second longest among active players.
Bengals 23, Steelers 20
At Cincinnati, Carson Palmer threw a 4-yard touchdown pass to Andre Caldwell with 14 seconds left, completing a nearly perfect drive that gave the Bengals a victory and ended the Steelers' nearly decade-long domination in Cincinnati.
Pittsburgh had won its last eight games on Cincinnati's home field.
Bears 25, Seahawks 19
At Seattle, Jay Cutler miserable Chicago debut two weeks ago became forgotten when he completed all three of his passes on Sunday's decisive drive. The third was for 36 yards to Devin Hester with 1:52 remaining, rallying the Bears to a victory over the Seahawks.
Seattle, playing without seven injured starters, drove to the Bears 29 with 30 seconds left. But Seneca Wallace, starting because quarterback Matt Hasselbeck was out with a broken rib, threw high and incomplete to Julius Jones on fourth-and-2 to seal the win for the Bears.
AP