formaldehyde, aspartame, and migraines, the first case series, Sharon E Jacob-Soo, Sarah A Stechschulte, UCSD, Dermatitis 2008 May: Rich Murray 2008.07.18http://rmforall.blogspot.com/2008_07_01_archive.htmFriday, July 18, 2008http://groups.yahoo.com/group/aspartameNM/message/1553Dermatitis. 2008 May-Jun; 19(3): E10-1.Formaldehyde, aspartame, and migraines: a possible connection.Jacob SE, Stechschulte S.Department of Dermatology and Cutaneous Surgery, University of Miami, Miami, FL, USA.Aspartame is a widely used artificial sweetener that has been linked to pediatric and adolescent migraines.Upon ingestion, aspartame is broken, converted, and oxidized into formaldehyde in various tissues.We present the first case series of aspartame-associated migraines related to clinically relevant positive reactions to formaldehyde on patch testing. PMID: 18627677formaldehyde from many sources, including aspartame, is major cause of Allergic Contact Dermatitis, SE Jacob, T Steele, G Rodriguez, Skin and Aging 2005 Dec.: Murray 2008.03.27http://rmforall.blogspot.com/2008_03_01_archive.htmThursday, March 27, 2008http://groups.yahoo.com/group/aspartameNM/message/1533"For example, diet soda and yogurt containing aspartame (Nutrasweet), release formaldehyde in their natural biological degradation.One of aspartame's metabolites, aspartic acid methyl ester, is converted to methanol in the body, which is oxidized to formaldehyde in all organs, including the liver and eyes. 22Patients with a contact dermatitis to formaldehyde have been seen to improve once aspartame is avoided. 22Notably, the case that Hill and Belsito reported had a 6-month history of eyelid dermatitis that subsided after 1 week of avoiding diet soda. 22"Sharon E. Jacob, MD, Assistant Professor of Medicine (Dermatology), University of California, San Diego 200 W. Arbor Drive #8420, San Diego, CA 92103-8420 Tel: 858-552-8585 ×3504 Fax: 305-675-8317 sjacob@contactderm.net;