Jo-Wilfried Tsonga lost before the third round of a Grand Slam tournament for the first time since 2007, surprised by 52nd-ranked Martin Klizan of Slovakia 6-4, 1-6, 6-1, 6-3 at the U.S. Open.
The No. 5-seeded Tsonga was drawn to face No. 3 Andy Murray in the quarterfinals at Flushing Meadows, but couldn't make it past the second round.
Tsonga was a Wimbledon semifinalist in July, then won a doubles silver medal for France at the Olympics.
Tsonga last failed to make it through two matches at a major when he lost to Andy Roddick in the first round of the 2007 Australian Open. Tsonga reached the 2008 Australian Open final.
Klizan never before reached the third round at a Grand Slam tournament.
In other matches, Former top-ranked players Ana Ivanovic and Jelena Jankovic of Serbia are quietly into the third round with impressive performances so far.
Each has dropped just nine games through two straight-set wins. The 12th-seeded Ivanovic beat 51st-ranked Sofia Arvidsson of Sweden 6-2, 6-2. Jankovic, seeded 30th, defeated 115th-ranked Lara Arruabarrena-Vecino of Spain 6-4, 6-2.
Both women reached No. 1 in the world in 2008, a breakthrough year for Serbian tennis when Ivanovic won the French Open and countryman Novak Djokovic took the Australian Open.
While Djokovic has since won four more Grand Slam titles, Ivanovic and Jankovic have often struggled in the last four years.
AP